5 Easy Facts About testosterone Described
5 Easy Facts About testosterone Described
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概括地說,雄激素助長蛋白質的合成及擁有雄激素受體的組織的生長,睪酮的效用可以分為合成代謝及雄性化效應。合成代謝效應包括肌肉質量及力量的增長、增加骨質密度及強度、刺激線性生長及骨骼成熟等。雄性化效應則包括性器官的成熟(尤其是陰莖及胎兒陰囊的生成)、出生後(通常是在青春期)聲線的轉沉、鬍鬚及體毛的生長等。這些效應一般都是男性的第二性徵。
肾上腺髓质: 肾上腺素、去甲肾上腺素 - 肾上腺皮质: 醛固酮、皮质醇、脱氢表雄酮
提神及提升體能(對照睪酮缺乏患者體能較佳,但與正常人無異,刻意補充對體能不會有顯著的增加)
由於睪酮能提升體能,一些運動員為保持體育狀態或表現,會於賽前使用睪酮。男運動員在賽前數小時,可以將睪酮注射陰囊內,激化身體的狀態。但現時大部份的體育項目都已把睪酮定為禁藥。
Testosterone is often a steroid within the androstane class containing a ketone plus a hydroxyl team at positions three and seventeen respectively. It's biosynthesized in many techniques from cholesterol and is particularly converted inside the liver to inactive metabolites.[8] It exerts its action by means of binding to and activation with the androgen receptor.[eight] In people and most other vertebrates, testosterone is secreted mostly through the testicles of males and, to the lesser extent, the ovaries of females.
在其他脊索动物的组织内也会有雄激素受体,而雄性及雌性对睾酮的反应也相当一致。在出生前雄性与雌性的睾酮剂量的差异,会导致在青春期或整个生命上的生物差异。
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用于多种男性性激素不足的状况 隐睾症、性腺功能减退症、阳痿及男性更年期。
成年男子不论服用或施打多少睾酮都无法再次促使阴茎的成长与发育(相反的,错误的使用激素,将可能造成体内原生激素紊乱,将无法自行生成使睾丸及阴茎萎缩,衍生出其他生殖系统疾病)
Outcomes prior to beginning are divided into two categories, categorized in relation towards the levels of growth.
睪酮芳構化成雌二醇會對腦及骨這兩個人體重要的組織構成主要的影響。在骨中,雌二醇加速了軟骨成長為骨的過程,使骨端接合及完成生長的程序。在中樞神經中,雌二醇是給予下視丘的主要迴饋訊號,尤其在影響排卵素的分泌。在很多哺乳動物的腦部中,某些性別差異區域在出生前或產期的雄性化,都是受著睪酮所產生的雌二醇影響,決定將來的雄性性行為。
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[70] This response engages penile reflexes (for instance erection and ejaculation) that assist in sperm Competitiveness when more than one male is present in mating encounters, making it possible for for more manufacture of productive sperm and a greater possibility of reproduction.
The connection involving testosterone and aggression can also function indirectly, as it has been proposed that testosterone does not amplify tendencies toward aggression, but fairly amplifies whatever tendencies will permit an individual to keep up social position when challenged. In many animals, aggression is the indicates of protecting social status. On the other hand, humans have many ways of obtaining standing. This may clarify why some studies discover a backlink between testosterone and pro-social conduct, if pro-social conduct is rewarded with social status. Hence the link among testosterone and aggression and violence is because of these staying rewarded with social position.[128] The connection may also be among a "permissive influence" whereby testosterone does elevate aggression concentrations, but only in the sense of permitting normal aggression amounts to get preserved; chemically or bodily castrating the individual will lower aggression concentrations (nevertheless not eliminate them) but Find out Why the person only requirements a small-degree of pre-castration testosterone to possess aggression ranges to return to regular, which they are going to keep on being at even when extra testosterone is added.